Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach

Tumour-associated macrophages, TAMs, play a pivotal role in tumour growth and metastasis by promoting tumour angiogenesis. Treatment with clodronate encapsulated in liposomes (clodrolip) efficiently depleted these phagocytic cells in the murine F9 teratocarcinoma and human A673 rhabdomyosarcoma mous...

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Dades bibliogràfiques
Autors principals: Zeisberger, S M, Odermatt, B, Marty, C, Zehnder-Fjällman, A H M, Ballmer-Hofer, K, Schwendener, R A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2006
Matèries:
Translational Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360657/
https://ncbi.nlm.nih.gov/pubmed/16832418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603240
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