Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.

Six recombinant human Fab fragments that were derived from the same human immunodeficiency virus type 1 (HIV-1)-infected individual and are directed against the CD4 binding site (CD4bs) of the gp120 envelope glycoprotein were studied. A range of neutralizing activity against the HIV-1 (HXBc2) isolat...

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書誌詳細
出版年:	J Virol
主要な著者:	Roben, P, Moore, J P, Thali, M, Sodroski, J, Barbas, C F, Burton, D R
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1994
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236421/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518527/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.8.4821-4828.1994
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Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.

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