Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.

Six recombinant human Fab fragments that were derived from the same human immunodeficiency virus type 1 (HIV-1)-infected individual and are directed against the CD4 binding site (CD4bs) of the gp120 envelope glycoprotein were studied. A range of neutralizing activity against the HIV-1 (HXBc2) isolat...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Roben, P, Moore, J P, Thali, M, Sodroski, J, Barbas, C F, Burton, D R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236421/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518527/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.8.4821-4828.1994
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