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Genetic heterogeneity and clonal evolution in neuroblastoma

Tumour heterogeneity and clonal evolution at the genetic level may explain the development of malignant or resistant disease during clinical progression of neuroblastoma (NB). In this report we use 1p allelic analysis and DNA ploidy to evaluate clonal heterogeneity and clonal selection in vivo. We s...

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Detalhes bibliográficos
Main Authors: Mora, J, Cheung, N-K V, Gerald, W L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364052/
https://ncbi.nlm.nih.gov/pubmed/11461074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1849
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