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Genetic Heterogeneity and Clonal Evolution of Tumor Cells and their Impact on Precision Cancer Medicine

The efficacy of targeted therapies in leukemias and solid tumors depends upon the accurate detection and sustained targeting of initial and evolving driver mutations and/or aberrations in cancer cells. Tumor clonal evolution of the diverse populations of cancer cells during cancer progression contri...

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Bibliografiske detaljer
Hovedforfatter: Sabaawy, Hatem E
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927925/
https://ncbi.nlm.nih.gov/pubmed/24558642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2329-6917.1000124
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