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Microdialysis and response during regional chemotherapy by isolated limb infusion of melphalan for limb malignancies

This study sought to use a microdialysis technique to relate clinical and biochemical responses to the time course of melphalan concentrations in the subcutaneous interstitial space and in tumour tissue (melanoma, malignant fibrous histiocytoma, Merkel cell tumour and osteosarcoma) in patients under...

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Detalhes bibliográficos
Main Authors: Thompson, J F, Siebert, G A, Anissimov, Y G, Smithers, B M, Doubrovsky, A, Anderson, C D, Roberts, M S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364039/
https://ncbi.nlm.nih.gov/pubmed/11461070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1902
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