Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion

This paper, for the first time, demonstrates that exposure of cells to the poly(ethylene oxide)-poly(propylene oxide) block copolymer, Pluronic P85, results in a substantial decrease in ATP levels selectively in MDR cells. Cells expressing high levels of functional P-glycoprotein (MCF-7/ADR, KBv; LL...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Batrakova, E V, Li, S, Elmquist, W F, Miller, D W, Alakhov, V Y, Kabanov, A V
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2001
Pynciau:
Regular Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364003/
https://ncbi.nlm.nih.gov/pubmed/11747344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2165
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg