Pancreatic tumours: molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumorigenesis

Alterations of K-ras, p53, p16 and DPC4/Smad4 characterize pancreatic ductal cancer (PDC). Reports of inactivation of these latter two genes in pancreatic endocrine tumours (PET) suggest that common molecular pathways are involved in the tumorigenesis of pancreatic exocrine and endocrine epithelia....

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Detalhes bibliográficos
Main Authors: Moore, P S, Orlandini, S, Zamboni, G, Capelli, P, Rigaud, G, Falconi, M, Bassi, C, Lemoine, N R, Scarpa, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363700/
https://ncbi.nlm.nih.gov/pubmed/11161385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1567
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