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Effect of P-glycoprotein on flavopiridol sensitivity

Flavopiridol is the first potent inhibitor of cyclin-dependent kinases (CDKs) to enter clinical trials. Little is known about mechanisms of resistance to this agent. In order to determine whether P-glycoprotein (Pgp) might play a role in flavopiridol resistance, we examined flavopiridol sensitivity...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Boerner, S A, Tourne, M E, Kaufmann, S H, Bible, K C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2001
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363628/
https://ncbi.nlm.nih.gov/pubmed/11355953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1688
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