Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitorD9331

Uracil DNA misincorporation and misrepair of DNA have been recognized as important events accompanying thymidylate synthase (TS) inhibition. dUTPase catalyses the hydrolysis of dUTP to dUMP, thereby maintaining low intracellular dUTP. We have addressed the relationship between dUTPase expression and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Webley, S D, Hardcastle, A, Ladner, R D, Jackman, A L, Aherne, G W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2000
Gaiak:
Regular Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363540/
https://ncbi.nlm.nih.gov/pubmed/10952785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1358
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