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Osteopontin is required for full expression of the transformed phenotype by the ras oncogene

The secreted phosphoprotein osteopontin (OPN) is strongly associated with the process of neoplastic transformation, based both on its pattern of expression in vivo and in vitro and on functional analyses. We have used 3T3 cells derived from wildtype and OPN-deficient mice and transformed by transfec...

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Detalhes bibliográficos
Main Authors: Wu, Y, Denhardt, D T, Rittling, S R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363489/
https://ncbi.nlm.nih.gov/pubmed/10901364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1200
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