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Osteopontin is required for full expression of the transformed phenotype by the ras oncogene
The secreted phosphoprotein osteopontin (OPN) is strongly associated with the process of neoplastic transformation, based both on its pattern of expression in vivo and in vitro and on functional analyses. We have used 3T3 cells derived from wildtype and OPN-deficient mice and transformed by transfec...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363489/ https://ncbi.nlm.nih.gov/pubmed/10901364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1200 |
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