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Glycerol restores p53-dependent radiosensitivity of human head and neck cancer cells bearing mutant p53
Mutation or inactivation of p53 is known to be present in approximately 50% of human cancers. We propose here a novel strategy for overcoming this problem in mutant p53-targeting cancer therapies. We examined the restoration of radiation-induced p53-dependent apoptosis by a chemical chaperone (glyce...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363451/ https://ncbi.nlm.nih.gov/pubmed/11104574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1511 |
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