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p53 alterations in recurrent squamous cell cancer of the head and neck refractory to radiotherapy

The aim of the study was to determine the incidence of p53 alterations by mutation, deletion or inactivation by mdm2 or human papillomavirus (HPV) infection in recurrent squamous cell cancer of the head and neck (SCCHN) refractory to radiotherapy. Twenty-two tumours were studied. The p53 status of e...

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Autors principals: Ganly, I, Soutar, D S, Brown, R, Kaye, S B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363290/
https://ncbi.nlm.nih.gov/pubmed/10646894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0932
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