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P53 germline mutations in childhood cancers and cancer risk for carrier individuals

The family history of cancer in children treated for a solid malignant tumour in the Paediatric Oncology Department at Institute Gustave-Roussy, has been investigated. In order to determine the role of germline p53 mutations in genetic predisposition to childhood cancer, germline p53 mutations were...

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Hlavní autoři: Chompret, A, Brugières, L, Ronsin, M, Gardes, M, Dessarps-Freichey, F, Abel, A, Hua, D, Ligot, L, Dondon, M-G, Paillerets, B Bressac-de, Frébourg, T, Lemerle, J, Bonaïti-Pellié, C, Feunteun, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363254/
https://ncbi.nlm.nih.gov/pubmed/10864200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1167
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