Germline SUFU mutation carriers and medulloblastoma: clinical characteristics, cancer risk, and prognosis

BACKGROUND: Germline mutations of suppressor of fused homolog (SUFU) predispose to sonic hedgehog (SHH) medulloblastoma. Germline SUFU mutations have been reported in nevoid basal cell carcinoma syndrome (NBCCS), but little is known about the cancer risk and clinical spectrum. METHODS: We performed...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Guerrini-Rousseau, Léa, Dufour, Christelle, Varlet, Pascale, Masliah-Planchon, Julien, Bourdeaut, Franck, Guillaud-Bataille, Marine, Abbas, Rachid, Bertozzi, Anne-Isabelle, Fouyssac, Fanny, Huybrechts, Sophie, Puget, Stéphanie, Bressac-De Paillerets, Brigitte, Caron, Olivier, Sevenet, Nicolas, Dimaria, Marina, Villebasse, Sophie, Delattre, Olivier, Valteau-Couanet, Dominique, Grill, Jacques, Brugières, Laurence
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Clinical Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280147/
https://ncbi.nlm.nih.gov/pubmed/29186568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox228
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