Germline SUFU mutation carriers and medulloblastoma: clinical characteristics, cancer risk, and prognosis

BACKGROUND: Germline mutations of suppressor of fused homolog (SUFU) predispose to sonic hedgehog (SHH) medulloblastoma. Germline SUFU mutations have been reported in nevoid basal cell carcinoma syndrome (NBCCS), but little is known about the cancer risk and clinical spectrum. METHODS: We performed...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Guerrini-Rousseau, Léa, Dufour, Christelle, Varlet, Pascale, Masliah-Planchon, Julien, Bourdeaut, Franck, Guillaud-Bataille, Marine, Abbas, Rachid, Bertozzi, Anne-Isabelle, Fouyssac, Fanny, Huybrechts, Sophie, Puget, Stéphanie, Bressac-De Paillerets, Brigitte, Caron, Olivier, Sevenet, Nicolas, Dimaria, Marina, Villebasse, Sophie, Delattre, Olivier, Valteau-Couanet, Dominique, Grill, Jacques, Brugières, Laurence
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
Soggetti:
Clinical Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280147/
https://ncbi.nlm.nih.gov/pubmed/29186568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox228
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