Depletion of protein kinase C (PKC) by 12- O -tetradecanoylphorbol-13-acetate (TPA) enhances platinum drug sensitivity in human ovarian carcinoma cells

Down-regulation of protein kinase C (PKC) by 12- O -tetradecanoylphorbol-13-acetate (TPA) enhances the sensitivity of human ovarian carcinoma 2008 cells to various types of platinum compounds such as cisplatin (DDP), carboplatin and (–)-(R)-2-aminomethylpyrrolidine (1,1-cyclobutanedicarboxylato)-pla...

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Main Authors: Isonishi, S, Ohkawa, K, Tanaka, T, Howell, S B
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2000
主題:
Regular Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363215/
https://ncbi.nlm.nih.gov/pubmed/10638963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0873
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