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Dual Function of Protein Kinase C (PKC) in 12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced Manganese Superoxide Dismutase (MnSOD) Expression: ACTIVATION OF CREB AND FOXO3a BY PKC-α PHOSPHORYLATION AND BY PKC-MEDIATED INACTIVATION OF Akt, RESPECTIVELY

12-O-tetradecanoylphorbol-13-acetate (TPA) has been shown to induce transcriptional activation of human manganese superoxide dismutase (MnSOD) mRNA in human lung carcinoma cells, A549, mediated by a protein kinase C (PKC)-dependent activation of cAMP-responsive element-binding protein (CREB)-1/ATF-1...

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Bibliografiske detaljer
Main Authors: Chung, Youn Wook, Kim, Ha Kun, Kim, Ick Young, Yim, Moon B., Chock, P. Boon
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191009/
https://ncbi.nlm.nih.gov/pubmed/21705328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.264945
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