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Mode of action of thiocoraline, a natural marine compound with anti-tumour activity

Thiocoraline, a new anticancer agent derived from the marine actinomycete Micromonospora marina, was found to induce profound perturbations of the cell cycle. On both LoVo and SW620 human colon cancer cell lines, thiocoraline caused an arrest in G1 phase of the cell cycle and a decrease in the rate...

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Detalles Bibliográficos
Main Authors: Erba, E, Bergamaschi, D, Ronzoni, S, Faretta, M, Taverna, S, Bonfanti, M, Catapano, C V, Faircloth, G, Jimeno, J, D'Incalci, M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363046/
https://ncbi.nlm.nih.gov/pubmed/10362104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690451
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