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Genetic alterations in hepatocellular carcinomas: association between loss of chromosome 4q and p53 gene mutations

The major risk factors for hepatocellular carcinomas (HCC) in high incidence areas include infection with hepatitis B and C viruses (HBV, HCV) and exposure to aflatoxin. Genetic alterations in 24 liver resection specimens from Shanghai and Qidong were studied. Hepatitis B virus was integrated in all...

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Bibliographic Details
Main Authors: Rashid, A, Wang, J-S, Qian, G-S, Lu, B-X, Hamilton, S R, Groopman, J D
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362990/
https://ncbi.nlm.nih.gov/pubmed/10389978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690321
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