PTEN/MMAC1 Mutation and Frequent Loss of Heterozygosity Identified in Chromosome 10q in a Subset of Hepatocellular Carcinomas

Frequent allelic losses on chromosome 10q have been reported in several types of cancers, suggesting the presence of a putative tumor suppressor gene(s) on the chromosomal arm. We examined loss of heterozygosity (LOH) on chromosome 10q in 37 hepatocellular carcinomas (HCC) using eleven dinucleotide...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Fujiwara, Yoshiyuki, Hoon, Dave S. B., Yamada, Terumasa, Umeshita, Koji, Gotoh, Mitsukazu, Sakon, Masato, Nishisho, Isamu, Monden, Morito
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926370/
https://ncbi.nlm.nih.gov/pubmed/10760687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00943.x
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