Loss of heterozygosity on chromosome 10q22-10q23 and 22q11.2-22q12.1 and p53 gene in primary hepatocellular carcinoma

AIM: To analyze loss of heterozygosity (LOH) and homozygous deletion on p53 gene (exon2-3, 4 and 11), chromosome 10q22-10q23 and 22q11.2-22q12.1 in human hepatocellular carcinoma (HCC). METHODS: PCR and PCR-based microsatellite polymorphism analysis techniques were used. RESULTS: LOH was observed at...

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Publicado no:World J Gastroenterol
Main Authors: Zhu, Guang-Neng, Zuo, Li, Zhou, Qing, Zhang, Su-Mei, Zhu, Hua-Qing, Gui, Shu-Yu, Wang, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572244/
https://ncbi.nlm.nih.gov/pubmed/15222050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i13.1975
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