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Differential outcomes in an extended family with constitutional t(11;22)(q23.3;q11.2)

The t(11;22) rearrangement is the most common recurrent familial reciprocal translocation in man. Heterozygote carriers are phenotypically normal but are at risk of subfertility in the male, miscarriages, and producing chromosomally unbalanced offspring. The unbalanced progeny usually results from a...

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Detalhes bibliográficos
Publicado no:J Pediatr Genet
Main Authors: Kee, Su Keyau, See, Valene Hsu-Lin, Chia, Patrick, Tan, Wei Ching, Tien, Sim Leng, Lim, Soon Tiong Alvin
Formato: Artigo
Idioma:Inglês
Publicado em: Georg Thieme Verlag KG 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020957/
https://ncbi.nlm.nih.gov/pubmed/27625838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/PGE-13046
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