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Differential outcomes in an extended family with constitutional t(11;22)(q23.3;q11.2)

The t(11;22) rearrangement is the most common recurrent familial reciprocal translocation in man. Heterozygote carriers are phenotypically normal but are at risk of subfertility in the male, miscarriages, and producing chromosomally unbalanced offspring. The unbalanced progeny usually results from a...

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Dettagli Bibliografici
Pubblicato in:J Pediatr Genet
Autori principali: Kee, Su Keyau, See, Valene Hsu-Lin, Chia, Patrick, Tan, Wei Ching, Tien, Sim Leng, Lim, Soon Tiong Alvin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Georg Thieme Verlag KG 2013
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020957/
https://ncbi.nlm.nih.gov/pubmed/27625838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/PGE-13046
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