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Prerequisites for effective isolated limb perfusion using tumour necrosis factor alpha and melphalan in rats

An isolated limb perfusion (ILP) model using soft tissue sarcoma-bearing rats was used to study prerequisites for an effective ILP, such as oxygenation of the perfusate, temperature of the limb, duration of the perfusion and concentration of tumour necrosis factor (TNF). Combination of 50 μg TNF and...

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Main Authors: Wilt, J H W de, Manusama, E R, Tiel, S T van, Ijken, M G A van, Hagen, T L M ten, Eggermont, A M M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362986/
https://ncbi.nlm.nih.gov/pubmed/10389992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690335
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