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In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug

The anti-tumour effects and mechanism of action of combretastatin A-4 and its prodrug, combretastatin A-4 disodium phosphate, were examined in subcutaneous and orthotopically transplanted experimental colon tumour models. Additionally, the ability of these compounds to directly interfere with endoth...

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Autors principals: Grosios, K, Holwell, S E, McGown, A T, Pettit, G R, Bibby, M C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362967/
https://ncbi.nlm.nih.gov/pubmed/10604728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6692174
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