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Determinants of anti-vascular action by combretastatin A-4 phosphate: role of nitric oxide

The anti-vascular action of the tubulin binding agent combretastatin A-4 phosphate (CA-4-P) has been quantified in two types of murine tumour, the breast adenocarcinoma CaNT and the round cell sarcoma SaS. The functional vascular volume, assessed using a fluorescent carbocyanine dye, was significant...

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Autors principals: Parkins, C S, Holder, A L, Hill, S A, Chaplin, D J, Tozer, G M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363526/
https://ncbi.nlm.nih.gov/pubmed/10952787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1361
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