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Potent interaction of flavopiridol with MRP1
The multidrug resistance protein 1 (MRP1) is an ATP-dependent transport protein for organic anions, as well as neutral or positively charged anticancer agents. In this study we show that flavopiridol, a synthetic flavonoid currently studied in phase 1 trials for its anti-proliferative characteristic...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
1999
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362861/ https://ncbi.nlm.nih.gov/pubmed/10496352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690687 |
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