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Rapid induction of p21(WAF1) but delayed down-regulation of Cdc25A in the TGF-β-induced cell cycle arrest of gastric carcinoma cells
Transforming growth factor-β (TGF-β) is a multifunctional polypeptide that inhibits cellular proliferation in most epithelial cells. cdk4 and several cyclin-dependent kinase (cdk) inhibitors (p15(INK4B), p21(WAF1/Cip1) and p27(Kip1)) have been implicated in the TGF-β-induced cell cycle arrest. More...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362369/ https://ncbi.nlm.nih.gov/pubmed/10376964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690478 |
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