Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases

Colorectal carcinomas (CRCs) with high microsatellite instability (MSI-H) share clinicopathological features distinctly different from their microsatellite stable (MSS) counterparts. Unlike MSS cancers, MSI-H CRCs occur predominantly in the right-sided colon and are often characterised by a strong l...

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Main Authors: Buckowitz, A, Knaebel, H-P, Benner, A, Bläker, H, Gebert, J, Kienle, P, von Knebel Doeberitz, M, Kloor, M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2005
主題:
Molecular Diagnostics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362037/
https://ncbi.nlm.nih.gov/pubmed/15856045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602534
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