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The development and characterisation of porphyrin isothiocyanate–monoclonal antibody conjugates for photoimmunotherapy

A promising approach to increase the specificity of photosensitisers used in photodynamic therapy has been through conjugation to monoclonal antibodies (MAb) directed against tumour-associated antigens. Many of the conjugations performed to date have relied on the activated ester method, which can l...

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Bibliografiske detaljer
Main Authors: Hudson, R, Carcenac, M, Smith, K, Madden, L, Clarke, O J, Pèlegrin, A, Greenman, J, Boyle, R W
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362018/
https://ncbi.nlm.nih.gov/pubmed/15812551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602517
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