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Mono- and tri-cationic porphyrin–monoclonal antibody conjugates: photodynamic activity and mechanism of action
Two cationic porphyrins bearing an isothiocyanate group for conjugation to monocolonal antibodies have been synthesized. The two porphyrins conjugated efficiently to three monoclonal antibodies (anti-CD104, anti-CD146 and anti-CD326), which recognize antigens commonly over-expressed on a range of tu...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045661/ https://ncbi.nlm.nih.gov/pubmed/21039468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03359.x |
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