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Epidermal growth factor receptor double targeting by a tyrosine kinase inhibitor (Iressa) and a monoclonal antibody (Cetuximab). Impact on cell growth and molecular factors
Among the recent advances in the molecular targeted therapy of cancer, the applications focused on epidermal growth factor receptor (EGFR) are currently the most promising and the most advanced at clinical level. In view of the different modes of action of monoclonal antibodies and tyrosine kinase i...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2005
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361947/ https://ncbi.nlm.nih.gov/pubmed/15756277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602428 |
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