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Epidermal growth factor receptor double targeting by a tyrosine kinase inhibitor (Iressa) and a monoclonal antibody (Cetuximab). Impact on cell growth and molecular factors

Among the recent advances in the molecular targeted therapy of cancer, the applications focused on epidermal growth factor receptor (EGFR) are currently the most promising and the most advanced at clinical level. In view of the different modes of action of monoclonal antibodies and tyrosine kinase i...

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Autors principals: Fischel, J-L, Formento, P, Milano, G
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361947/
https://ncbi.nlm.nih.gov/pubmed/15756277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602428
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