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Epidermal growth factor receptor double targeting by a tyrosine kinase inhibitor (Iressa) and a monoclonal antibody (Cetuximab). Impact on cell growth and molecular factors

Among the recent advances in the molecular targeted therapy of cancer, the applications focused on epidermal growth factor receptor (EGFR) are currently the most promising and the most advanced at clinical level. In view of the different modes of action of monoclonal antibodies and tyrosine kinase i...

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Detalhes bibliográficos
Main Authors: Fischel, J-L, Formento, P, Milano, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361947/
https://ncbi.nlm.nih.gov/pubmed/15756277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602428
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