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MET signalling in primary colon epithelial cells leads to increased transformation irrespective of aberrant Wnt signalling

It has been shown that in hereditary and most sporadic colon tumours, components of the Wnt pathway are mutated. The Wnt target MET has been implicated in the development of colon cancer. Here, we show that overexpression of wild-type or a constitutively activated form of MET in colon epithelial cel...

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Bibliografische gegevens
Hoofdauteurs: Boon, E M J, Kovarikova, M, Derksen, P W B, van der Neut, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361927/
https://ncbi.nlm.nih.gov/pubmed/15785735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602405
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