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Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis

The death ligand TRAIL (Apo2L) has potential for cancer therapy, since tumour cells are thought to be more sensitive than normal cells. We investigated whether sensitivity to TRAIL increases during the adenoma to carcinoma transition of colorectal carcinogenesis. Under the same culture conditions, w...

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Bibliographic Details
Main Authors: Hague, A, Hicks, D J, Hasan, F, Smartt, H, Cohen, G M, Paraskeva, C, MacFarlane, M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361885/
https://ncbi.nlm.nih.gov/pubmed/15685228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602387
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