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Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis

The death ligand TRAIL (Apo2L) has potential for cancer therapy, since tumour cells are thought to be more sensitive than normal cells. We investigated whether sensitivity to TRAIL increases during the adenoma to carcinoma transition of colorectal carcinogenesis. Under the same culture conditions, w...

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Main Authors: Hague, A, Hicks, D J, Hasan, F, Smartt, H, Cohen, G M, Paraskeva, C, MacFarlane, M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361885/
https://ncbi.nlm.nih.gov/pubmed/15685228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602387
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