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Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis

The death ligand TRAIL (Apo2L) has potential for cancer therapy, since tumour cells are thought to be more sensitive than normal cells. We investigated whether sensitivity to TRAIL increases during the adenoma to carcinoma transition of colorectal carcinogenesis. Under the same culture conditions, w...

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Detalhes bibliográficos
Main Authors: Hague, A, Hicks, D J, Hasan, F, Smartt, H, Cohen, G M, Paraskeva, C, MacFarlane, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361885/
https://ncbi.nlm.nih.gov/pubmed/15685228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602387
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