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Evaluation of the fibroblast growth factor system as a potential target for therapy in human prostate cancer

Overexpression of fibroblast growth factors (FGFs) has been implicated in prostate carcinogenesis. FGFs function via their high-affinity interactions with receptor tyrosine kinases, FGFR1–4. Expression of FGFR1 and FGFR2 in prostate cancer (CaP) was not found to be associated with clinical parameter...

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Detalhes bibliográficos
Main Authors: Gowardhan, B, Douglas, D A, Mathers, M E, McKie, A B, McCracken, S R C, Robson, C N, Leung, H Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361833/
https://ncbi.nlm.nih.gov/pubmed/15655558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602274
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