Similar expression to FGF (Sef) inhibits fibroblast growth factor-induced tumourigenic behaviour in prostate cancer cells and is downregulated in aggressive clinical disease

BACKGROUND: The fibroblast growth factor (FGF) axis is an important mitogenic stimulus in prostate carcinogenesis. We have previously reported that transcript level of human similar expression to FGF (hSef), a key regulator of this pathway, is downregulated in clinical prostate cancer. In this study...

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Autors principals: Darby, S, Murphy, T, Thomas, H, Robson, C N, Leung, H Y, Mathers, M E, Gnanapragasam, V J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788253/
https://ncbi.nlm.nih.gov/pubmed/19888221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605379
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