Mitogenic growth signalling, DNA replication licensing, and survival are linked in prostate cancer

Activation of mitogen/extracellular-signal-regulated kinase kinase 5/extracellular signal-regulated kinase-5 (MEK5/ERK5) growth signalling is coupled to increased cell proliferation in prostate cancer (PCa). Dysregulation of the DNA replication licensing pathway, a critical step in growth control do...

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Bibliografiska uppgifter
Huvudupphovsmän: Dudderidge, T J, McCracken, S R, Loddo, M, Fanshawe, T R, Kelly, J D, Neal, D E, Leung, H Y, Williams, G H, Stoeber, K
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2007
Ämnen:
Molecular Diagnostics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360172/
https://ncbi.nlm.nih.gov/pubmed/17406359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603718
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