Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma

Epidermal growth factor receptor (EGFR) and tumour growth factor alpha (TGFα) are frequently overexpressed in renal cell carcinoma (RCC) yet responses to single-agent EGFR inhibitors are uncommon. Although von Hippel–Lindau (VHL) mutations are predominant, RCC also develops in individuals with tuber...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gemmill, R M, Zhou, M, Costa, L, Korch, C, Bukowski, R M, Drabkin, H A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361810/
https://ncbi.nlm.nih.gov/pubmed/15956968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602646
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados