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Determination of the consequences of VHL mutations on VHL transcripts in renal cell carcinoma

Genetic and epigenetic changes in the von Hippel-Lindau (VHL) tumour suppressor gene are common in sporadic conventional (clear cell) renal cell carcinoma (ccRCC). The effects on VHL expression are unknown but increased understanding may be relevant clinically, either in terms of prognosis or in the...

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Autores principales: TAYLOR, CLAIRE, CRAVEN, RACHEL A., HARNDEN, PATRICIA, SELBY, PETER J., BANKS, ROSAMONDE E.
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583750/
https://ncbi.nlm.nih.gov/pubmed/22825683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1561
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