Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS

In contrast to cutaneous melanoma, there is no evidence that BRAF mutations are involved in the activation of the mitogen-activated protein kinase (MAPK) pathway in uveal melanoma, although there is increasing evidence that this pathway is activated frequently in the latter tumours. In this study, w...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zuidervaart, W, van Nieuwpoort, F, Stark, M, Dijkman, R, Packer, L, Borgstein, A-M, Pavey, S, van der Velden, P, Out, C, Jager, M J, Hayward, N K, Gruis, N A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2005
Sujets:
Molecular Diagnostics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361800/
https://ncbi.nlm.nih.gov/pubmed/15928660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602598
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