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p53 polymorphisms associated with mutations in and loss of heterozygosity of the p53 gene in male oral squamous cell carcinomas in Taiwan

The present study was designed to examine whether different p53 haplotypes of exon 4–intron 3–intron 6 affect the frequency of mutations and loss of heterozygosity (LOH) of the p53 gene in male oral squamous cell carcinomas (OSCCs) in Taiwan. We found that individuals without two Pro-W-G alleles had...

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Detalhes bibliográficos
Main Authors:	Hsieh, L-L, Huang, T-H, Chen, I-H, Liao, C-T, Wang, H-M, Lai, C-H, Liou, S-H, Chang, J T-C, Cheng, A-J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2005
Assuntos:	Clinical Study
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2361746/ https://ncbi.nlm.nih.gov/pubmed/15583690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602271
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p53 polymorphisms associated with mutations in and loss of heterozygosity of the p53 gene in male oral squamous cell carcinomas in Taiwan

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