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Clinical anticancer drug development: targeting the cyclin-dependent kinases

Cell division involves a cyclical biochemical process composed of several step-wise reactions that have to occur once per cell cycle. Dysregulation of cell division is a hallmark of all cancers. Genetic and epigenetic mechanisms frequently result in deranged expression and/or activity of cell-cycle...

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Detalhes bibliográficos
Main Authors: Benson, C, Kaye, S, Workman, P, Garrett, M, Walton, M, de Bono, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361734/
https://ncbi.nlm.nih.gov/pubmed/15558073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602229
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