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Reorganisation of Wnt-response pathways in colorectal tumorigenesis
In most colorectal tumours, APC mutation stabilises β-catenin and mimics elements of Wnt growth factor signalling, but the high frequency of epigenetic loss of Wnt antagonists indicates an additional role for ligand-mediated Wnt signalling. Here, we have investigated the expression of key components...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361695/ https://ncbi.nlm.nih.gov/pubmed/18414471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604327 |
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