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Expression of the 5T4 oncofoetal antigen in renal cell carcinoma: a potential target for T-cell-based immunotherapy

The 5T4 oncofoetal antigen is a heavily glycosylated cell surface protein found on human placental trophoblast and on diverse types of human cancer but is not expressed at significant levels on adult human tissues in health. It therefore satisfies the criteria for a tumour-associated antigen and is...

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Autori principali: Griffiths, R W, Gilham, D E, Dangoor, A, Ramani, V, Clarke, N W, Stern, P L, Hawkins, R E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361613/
https://ncbi.nlm.nih.gov/pubmed/16222313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602776
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