Characterization of the murine 5T4 oncofoetal antigen: a target for immunotherapy in cancer.

Human 5T4 oncofoetal antigen defined by the murine 5T4 monoclonal antibody is a highly glycosylated protein expressed by trophoblast and a few specialized adult epithelia. Up-regulation of 5T4 expression in some cancers is associated with poor clinical outcome; overexpression of human 5T4 cDNA in ep...

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Autori principali: Woods, Andrew M, Wang, Who W, Shaw, David M, Ward, Christopher M, Carroll, Miles W, Rees, Buddug R, Stern, Peter L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222756/
https://ncbi.nlm.nih.gov/pubmed/12003637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020104
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