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Expression of the 5T4 oncofoetal antigen in renal cell carcinoma: a potential target for T-cell-based immunotherapy

The 5T4 oncofoetal antigen is a heavily glycosylated cell surface protein found on human placental trophoblast and on diverse types of human cancer but is not expressed at significant levels on adult human tissues in health. It therefore satisfies the criteria for a tumour-associated antigen and is...

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Detalhes bibliográficos
Main Authors: Griffiths, R W, Gilham, D E, Dangoor, A, Ramani, V, Clarke, N W, Stern, P L, Hawkins, R E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361613/
https://ncbi.nlm.nih.gov/pubmed/16222313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602776
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