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DNA replication licensing and cell cycle kinetics of normal and neoplastic breast

Mcm2–7 (MCM) proteins are part of the origin licensing machinery that regulates initiation of DNA replication. Geminin is a licensing repressor and prevents reinitiation of DNA replication during S–G2–M phase by blocking reloading of Mcm2–7 at replication origins. Here, we have analysed these replic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shetty, A, Loddo, M, Fanshawe, T, Prevost, A T, Sainsbury, R, Williams, G H, Stoeber, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361513/
https://ncbi.nlm.nih.gov/pubmed/16278669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602829
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